We observed an increasing trend in labeled glucose and glycolytic intermediates including pyruvate (M+3) and lactate (M+3) in both erythrocytes and the inner ear from 1 month-old up to 16-month-old mice ( Figures 1 E–1G).
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Metabolic shifts in murine inner ears mimicking erythrocytes and plasma reveal diagnostics and early predictors for age-related hearing loss.
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