Epidemiologic consequences of preclinical transmission of foot-and-mouth disease virus in cattle.

The overall model was highly significant [ F (7, 3,992) = 371.3, p < 2.2 × 10 –16 ] and accounted for approximately 39% of the variance in log-transformed cattle infections.

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The interaction between preclinical duration and response strategy was significant for preclinical infectious durations of 2 (β = −0.11, p = 0.045) and 3 days (β = −0.40, p < 2.9 × 10 –12 ), suggesting that the mitigating effect of an optimal response becomes more pronounced as the preclinical phase lengthens; however, the interaction for a preclinical phase duration of 1 day was marginally non-significant ( p = 0.097).

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