Barely Significant
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The Effect of Glucocorticoid and Mineralocorticoid Receptor Antagonists in the Skin of Aged Female Mice.

Int J Mol Sci · 2025 · PMC12427858 · PMID 40943265

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did not achieve significanceno p-value reported
This result suggests a possible compensatory upregulation of GR when MR is inhibited compared with dual GR/MR inhibition, which leads to a decreased expression of Nr3c1 (that did not achieve significance relative to expression upon vehicle treatment).

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