Parkinson's Disease Through the Lens of Metabolomics: A Targeted Systematic Review on Human Studies (2019-2024).

J Clin Med · 2025 · PMC12429492 · PMID 40944038

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highly significantno p-value reported

This analysis highlighted xanthine metabolites ( inosine, xanthosine, xanthine, and hypoxanthine) as highly significant and predictive for PD, showing a consistent pattern of increased abundance in de novo patients compared to controls.

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