Interleukin Networks in GVHD: Mechanistic Crosstalk, Therapeutic Targeting, and Emerging Paradigms.

Int J Mol Sci · 2025 · PMC12429620 · PMID 40943537

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Consequently, polymorphisms within the IL-1 gene—particularly the variable number of tandem repeats (VNTR) polymorphism of IL-1Ra—may be significant for donor selection and could contribute to optimizing GVHD prophylaxis and therapeutic outcomes [ 30 ].

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