highly significantp < 0.0001
Two-way ANOVA revealed highly significant main effects of both cell type (F 1,14 = 89.42, p < 0.0001) and ZnO concentration (F 3,14 = 11.00, p < 0.001), with no significant interaction effect (F 3,14 = 1.25, p = 0.326), indicating that the differential sensitivity pattern remains consistent across all tested concentrations.