Sex differences in the association of planetary health diet, genetic risk, with overall cancer incidence: a prospective study from UK Biobank.

Int J Surg · 2025 · PMC12430732 · PMID 40552888

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borderline significantno p-value reported

In the multivariable-adjusted model, participants in the highest quintile of PHD adherence showed a borderline significant reduction in overall cancer risk (hazard ratio [HR]: 0.95, 95% confidence intervals [CI]: 0.90–1.00) relative to the lowest quintile.

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borderline significanceno p-value reported

This may explain the slight inconsistency between the borderline significance observed in the highest quintile and the significant per-SD association, as categorization into quintiles can lead to information loss compared with continuous modeling.

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