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Rational design of an epitope-centric vaccine against <i>Pseudomonas aeruginosa</i> using pangenomic insights and immunoinformatics approach.

Front Immunol · 2025 · PMC12434008 · PMID 40959094

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an increasing trendno p-value reported
Figure 9C illustrates the dynamics of the B-cell population, exhibiting an increasing trend in memory B cells and a shift in isotype expression from IgM to IgG, which further validates class switching and the generation of long-lasting humoral memory.

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