Barely Significant
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Serum Concentration of Apixaban in Relation to Renal Function in Older Hospitalized Patients.

Drugs Aging · 2025 · PMC12436539 · PMID 40707719

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highly significantno p-value reported
The findings show that renal function is a highly significant and major predictor of apixaban clearance in older patients and suggest that in patients with GFR < 30 ml/ml, dosing should be reduced by more than 50%, which is recommended in apixaban’s product information.

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