Mendelian randomization study: Metabolites as mediators of inflammatory factors in ulcerative colitis.

Medicine (Baltimore) · 2025 · PMC12440496 · PMID 40958322

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

marginally significantP = .051so close (0.05 < p ≤ 0.1)

Moreover, 1-arachidonoyl-GPC has a marginally significant protective effect ( P = .051), potentially through the cyclooxygenase pathway, which generates prostaglandins to balance inflammatory responses.

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