Trends in baseline blood lipid levels in randomized placebo-controlled trials of overweight or obesity from 1990 to 2024.

World J Diabetes · 2025 · PMC12444302 · PMID 40980309

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a notable trendno p-value reported

However, a sex-stratified analysis did not reveal a notable trend in TC and LDL-C levels in male-predominant studies (TC: Rs = -0.338, P adj = 0.078, I 2 = 99.8%; LDL-C: Rs = -0.340, P adj = 0.089, I 2 = 98.0%, Figure 5J and K ).

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