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Hemoglobin Oxygen Affinity Does Not Change in the Canine Model of Moderate Acute Normovolemic Hemodilution.

ACS Omega · 2025 · PMC12444557 · PMID 40978449

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a decreasing trendno p-value reported
an increasing trendno p-value reported
However, the theoretical oxygen-release capacity exhibited an increasing trend, whereas the Hill coefficient exhibited a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.