The Protective Effects of SGLT-2 Inhibitors Against Postoperative Acute Kidney Injury in Type 2 Diabetes.

Kidney Int Rep · 2025 · PMC12446964 · PMID 40980648

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a decreasing trendno p-value reported

Although a decreasing trend in clinical practice patterns regarding perioperative SGLT-2i discontinuation were observed following the guideline update (data not shown), the absence of DKA cases after 2021 suggests increased clinical awareness and caution regarding the risk of SGLT-2i–associated DKA in the perioperative setting.

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