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Results of the Global Burden of Disease study for schizophrenia: trends from 1990 to 2021 and projections to 2050.

Front Psychiatry · 2025 · PMC12447577 · PMID 40980052

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an increasing trendno p-value reported
3.3 Age and gender specific burden of schizophrenia From 1990-2021, there is an increasing trend in the incidence and prevalence of schizophrenia in both males and females globally, and both incidence and prevalence are higher in males than in females, see Figure 5 .

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a decreasing trendno p-value reported
The prevalence of schizophrenia in males and females peaks in the 35–39 age group and then shows a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.