Barely Significant
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Analysis of global, regional and national trends in the burden of soft tissue and other extraosseous sarcomas from 1990 to 2021: A systematic analysis of the global burden of disease study 2021.

PLoS One · 2025 · PMC12449004 · PMID 40971981

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an increasing trendno p-value reported
3.4 Joinpoint regression analysis of trends in soft tissue and other extraosseous sarcomas For the ASIR of STSES, the AAPC from 1990 to 2021 was −0.13 (−0.22,0.04), with an increasing trend globally from 1990 to 1995, then flat from 1995 to 2002, 2002–2008, a slight decrease from 2008 to 2013, and an increasing trend from 2013 to 2018; 2018–2021 showed the most significant decline with an Annual Percentage Change (APC) of −1.43 (−1.89, 0.96).

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