Changes in Neural Activities and Neuroplasticity Related to Nonpharmacological Interventions for Major Depressive Disorder: A Systematic Literature Review.

Biol Psychiatry Glob Open Sci · 2025 · PMC12455126 · PMID 40994837

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a nonsignificant trendno p-value reported

Both studies found a significant decrease in MDD symptoms posttreatment, and one found a nonsignificant trend associating MDD symptom change with the amygdala’s functional connectivity with the dorsolateral PFC and dorsal ACC.

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