Impact of study design, contamination, and data characteristics on results and interpretation of microbiome studies.

To determine how contamination influenced the number of differentially abundant taxa, we quantified the proportion of significant hits that were contaminants, borderline significant (false discovery rate-corrected P value [FDR] between 0.05 and 0.1 in the uncontaminated data set), or random (FDR > 0.1 in the uncontaminated data set).

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