Barely Significant
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Altered carnitine-acylcarnitine profiles in levothyroxine-treated congenital hypothyroid patients with fatigue: An LC-MS/MS-based study from Bangladesh.

PLoS One · 2025 · PMC12463203 · PMID 40996983

1
hedged sentence
0.0490
closest p · 1.0× alpha
0.0490
boldest claim

The sentences

borderline significanceP=0.049actually significant
Statistical Power and Interpretation: The sample size for the patient group (n=56) is small, and while the control group is larger (n=107), the study would benefit from power calculations to justify its ability to detect the reported effects, particularly for metabolites with borderline significance (e.g., P=0.049).

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