Ketone body supplementation in keto-adapted mice reveals metabolic adaptations and glycogen-independent exercise capacity.

For Acox1 , an increasing trend is found between KD+BHB and KD (Figure 1d ). 3.3 Chronic ketone body supplementation activates AMPK but not mTOR in liver and gastrocnemius muscle AMPK and mTOR are key regulators of cellular energy metabolism and growth, respectively.

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