Confocal Raman microspectroscopy for spatially resolved tissue characterisation of disease-linked spectra-pathological signatures.

42 More specifically, when breast tissue transformed from healthy to advanced cancer, the normalised peak intensity of tryptophan (at 754 cm −1 ) displayed an increasing trend between healthy and cancer samples and then slowly decreased after tumour progression, which may be linked to the modulation of tumour cell proliferation. 42 The phenylalanine peak (at 1003 cm −1 ) showed a similar changing pattern as the tryptophan peak; however, the intensity of the decreasin

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