Single-Cell transcriptomic profiles of peripheral blood immune cells reveal early monocyte and platelet activation in the transition from high-risk states to clinical sepsis.

Sci Rep · 2025 · PMC12464160 · PMID 40998960

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an increasing trendno p-value reported

The four-gene signature (S100A8/A9, IFITM2/3) in this cohort was primarily active in monocytes and showed an increasing trend in elderly T2DM patients compared to healthy elderly controls (Fig. 6 c).

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