Role of hyaluronan in endometrial receptivity: key insights for implantation and reproductive success.

A decreasing trend in the expression of ITH4 and ITIH5 occurred from the proliferative phase to the mid-secretory phase (Fig. 8 A-B; GEO datasets A and B).

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An increasing trend of HA surface receptor CD44 gene expression (Fig. 5 ) was present during the menstrual cycle (Fig. 9 ), and its expression correlated positively with that of other cell surface HA receptors, including syndecan 1, syndecan 3 and the ECM receptor versican, but negatively with that of the HA receptor glypican 2 and the ECM receptor tenascin C throughout the menstrual cycle (GEO datasets A and B; Fig. 9 ).

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