A worrying trend is the high antibiotic resistance of S. pneumoniae , which has continued to rise in recent years in Bulgaria and different geographic regions [ 30 , 31 , 32 , 33 ].
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Population Genetic Structure of Invasive and Non-Invasive <i>Streptococcus pneumoniae</i> Isolates After Fifteen Years of Routine PCV10 Vaccination in Bulgaria.
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