Even if 6 of 8 subjects show the effect, however (and ignoring multiple comparisons), the p-value of a one-sided binomial test is not significant at the 0.05 level (7 of 8 subjects is barely significant).
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Even if 6 of 8 subjects show the effect, however (and ignoring multiple comparisons), the p-value of a one-sided binomial test is not significant at the 0.05 level (7 of 8 subjects is barely significant).