Isoliquiritigenin as a Neuronal Radiation Mitigant: Mitigating Radiation-Induced Anhedonia Tendency Targeting Grik3/Grm8/Grin3a via Integrated Proteomics and AI-Driven Discovery.

Pharmaceuticals (Basel) · 2025 · PMC12472569 · PMID 41011178

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KEGG pathway enrichment analysis ( Figure 8 D) shows highly significant involvement in glutamatergic synapse regulation (Grin3a, Gng10, Grm8, Prkaca, Grik3), SNARE-mediated vesicular transport (Stx17, Vamp2, Vti1b), and synaptic vesicle cycling (Vamp2).

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