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An Overview of the Epidemiology of Multidrug Resistance and Bacterial Resistance Mechanisms: What Solutions Are Available? A Comprehensive Review.

Microorganisms · 2025 · PMC12472688 · PMID 41011524

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an increasing trendno p-value reported
In Europe, data provided by the European Centre for Disease Prevention and Control (ECDC) indicate an increasing trend in resistance to third-generation cephalosporins and carbapenems among Klebsiella pneumoniae (with carbapenem resistance exceeding 25% in 33% of reporting countries) and Escherichia coli .

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