The statistical significance of the discovered motifs is assessed using the E-value, with lower values indicating higher confidence; in our analysis, the top motifs showed extremely significant E-values ranging from 5.7 × 10 −128 to 6.7 × 10 −127 [ 13 ].
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HPV as a Molecular Hacker: Computational Exploration of HPV-Driven Changes in Host Regulatory Networks.
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