Oxidatively damaged DNA in DNA repair-deficient and ethanol-exposed fetal brains induces gene dysregulation and mitochondrial dysfunction associated with neurodevelopmental disorders.

Redox Biol · 2025 · PMC12478066 · PMID 40972158

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hedged sentences

0.0001

closest p · 0.0× alpha

0.0520

boldest claim

The sentences

highly significantp < 0.0001actually significant

5 D), and conversely highly significant decreases in both the maximal respiration (p < 0.0001) ( Fig. 5 E) and spare respiration capacity (p < 0.0001) ( Suppl.

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a trend toward significancep = 0.052so close (0.05 < p ≤ 0.1)

In the LTM underpass task, there was a significant main effect of Ogg1 genotype (F(1,34) = 4.70, p < 0.05), a significant main effect of EtOH exposure (F(1,34) = 5.27, p < 0.05), and a trend toward significance for the interaction (F(1,34) = 6.52, p = 0.052).

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