Twenty-year trend of thyrotoxicosis and thyrotoxic periodic paralysis: a population-based cohort study.

Eur Thyroid J · 2025 · PMC12478295 · PMID 40911544

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0120

boldest claim

The sentences

a decreasing trendP < 0.001actually significant

The proportion of patients with TPP remained steady from 2002 to 2016, followed by a decreasing trend from 2016 to 2021 (whole sample: APC −21.436%; 95% CI: −48.877 to −9.21; P < 0.001; male: APC −22.12%; 95% CI: −43.163 to −10.906; P < 0.001).

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an increasing trendP = 0.012actually significant

2), with an increasing trend indicated by linear ( P = 0.012; Table 3 ) and joinpoint (AAPC 5.229%; 95% CI: 0.9–8.455; P = 0.018; Table 4 ) regression.

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