Heatmap results indicate a notable trend of gene up-regulation across stages I-IV in CXCR1, CXCR2, CXCR4, CXCR5, and CXCR7, with CXCR7 showing stable expression at different stages of OS (Fig. 2 D).
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C-X-C chemokine receptor family genes in osteosarcoma: expression profiles, regulatory networks, and functional impact on tumor progression.
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