BRD4 inhibition leads to MDSC apoptosis and enhances checkpoint blockade therapy.

J Clin Invest · 2025 · PMC12483567 · PMID 40762981

Europe PMC DOI

hedged sentence

0.3900

closest p · 7.8× alpha

0.3900

boldest claim

The sentences

did not achieve significanceP = 0.39not close (p > 0.1)

2.0 × 10 6 , P < 0.001), but the reduction of MDSCs in BRD4 cKO mice receiving PLX51107 did not achieve significance (4.22 × 10 6 vs. 1.53 × 10 6 , P = 0.39) ( Figure 3E ).

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