A histone-centric multi-omics study shows that increased H3K4 methylation sustains triple-negative breast cancer phenotypes.

Nat Commun · 2025 · PMC12484688 · PMID 41028718

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a decreasing trendno p-value reported

OICR-9429-treated cells showed a decreasing trend in H3K4me2 levels and a corresponding reduced gene expression in 8 of the 10 genes tested (Supplementary Fig. 10b, c ).

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