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Balancing benefit and risk: clinical considerations in the use of acetaminophen, non-steroidal anti-inflammatory drugs, and dexamethasone for perioperative multimodal analgesia.

Korean J Pain · 2025 · PMC12485475 · PMID 40527754

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an increasing trendno p-value reported
Another analysis of data from 2006 to 2016 regarding total hip replacement and total knee replacement revealed an increasing trend in the utilization of two or more modes of multimodal analgesia over the decade.

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