Farnesiferol C enhances the effects of chemotherapy and ionising radiation in human melanoma cells via targeting topoisomerase II alpha.

J Enzyme Inhib Med Chem · 2025 · PMC12486455 · PMID 41026084

Europe PMC DOI

hedged sentence

0.0730

closest p · 1.5× alpha

0.0730

boldest claim

The sentences

marginally non-significantp = 0.073so close (0.05 < p ≤ 0.1)

The log-rank test yielded a marginally non-significant difference between groups ( p = 0.073), with a hazard ratio of 1.3, indicating a trend towards reduced survival associated with elevated TOP2A expression in SKCM.

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