EZH2-mediated H3K27me3 links microbial inosine loss to depression: a gut-brain epigenetic switch.

Theranostics · 2025 · PMC12486992 · PMID 41041075

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a weak trendno p-value reported

Neuronal-specific EZH2 knockout exhibited only a weak trend toward improvement in gut microbiota—mediated anxiety-like behaviors, suggesting a potential, albeit limited, link between EZH2 and anxiety phenotypes.

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