An upward trend in the age-standardized rate could be identified if the APC and its 95% CI are both > 0, and if they were both < 0, the age-standardized rate was deemed to present a decreasing trend.
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Global trends and regional differences of hepatoblastoma: a systematic analysis and predictions to 2035 based on the global burden of disease study 2021.
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On the contrary, the incidence rate presents an increasing trend in low SDI and low-middle SDI, and the highest predicted incidence rate occurs in the low SDI regions (0.036) (Fig. 6 C).