Barely Significant
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Endurance training increases a ubiquitylated form of histone H3 in the skeletal muscle, supporting Notch1 upregulation in an MDM2-dependent manner.

J Physiol · 2025 · PMC12487604 · PMID 40911795

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

extremely significantP = 0.0002actually significant
11 H ), it had an extremely significant effect on the level of H3K27 me3 detected at 25 kDa (Fig. 11 I , P = 0.0002, −21%).

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