Consistently, we noted an increased expression of iCAF marker genes (Elyada et al, 2019 ) and a decreasing trend of the myCAF ones (Elyada et al, 2019 ; Chen et al, 2023 ) (Fig. 3F ).
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Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer.
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Interestingly, the iCAF markers PDGFRα, Lamin A/C and PDPN showed an increasing trend following exposure to Fn (Fig. 3D ; Appendix Fig.