Internet-based indicated prevention of anxiety and depression disorder onset three-arm randomized clinical trial.

NPJ Digit Med · 2025 · PMC12489038 · PMID 41034558

Europe PMC DOI

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closest p · 1.0× alpha

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boldest claim

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borderline significancep = 0.05actually significant

Exploratory analyses revealed effects on cumulative incidence of anxiety (HR = 0.48 IG-IMI, HR = 0.32 AG-IMI) and depressive disorders (HR = 0.61 AG-IMI), though for depression, IG-IMI reached only borderline significance ( p = 0.05, HR = 0.48).

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