Genetic variation at PPM1H predicts mobilization efficiency in stem cell donors.

Blood Adv · 2025 · PMC12496232 · PMID 40644613

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highly significantno p-value reported

10 , 11 , 15 In conclusion, we have previously reported an inverse relationship between PPM1H activity and blood CD34 + cell levels, supported by a highly significant genetic association, gene expression data in CD34 + cells, and ex vivo knockdown studies in primary human CD34 + cells.

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