From a clinical perspective, variations in CYP2C19 metabolic activity are highly significant, as reduced enzyme function can result in elevated plasma concentrations of CYP2C19 -substrate medications, thereby increasing the risk of adverse drug reactions or diminished therapeutic efficacy.
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Prevalence of <i>CYP2C19</i> Poor Metabolisers Among South Indian Psychiatric Patients: A Pharmacogenetic Perspective Toward Precision Psychopharmacology.
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