What is even more concerning is that an increasing trend of CRE strains producing dual carbapenemases, typically KPC-2 and NDM-1, has been reported widely over the past 5 years ( 4 – 8 ).
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High transconjugation efficiency of fusion plasmid pNDM_KPC in carbapenem-resistant <i>Citrobacter freundii</i> and its formation driven by IS<i>26</i>-mediated integration.
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