Barely Significant
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Global burden of polycystic ovary syndrome in women of reproductive age, 1990-2021: Analysis of the global burden of disease study 2021 with projections to 2050.

PLoS One · 2025 · PMC12503323 · PMID 41056244

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a decreasing trendno p-value reported
Conversely, a decreasing trend was observed in the 20–24 and 25–29 age groups, with the most significant decline occurring in the 20–24 age group (1.75%) ( S1 Fig ).

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an increasing trendno p-value reported
Notably, the incidence of PCOS in women showed an increasing trend in the age groups of 15–19, 30–34, 35–39, 40–44, and 45–49 years, with the most substantial increase observed in the 15–19 age group (27.00%).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.