Engineering of mRNA vaccine platform with reduced lipids and enhanced efficacy.

Nat Commun · 2025 · PMC12504719 · PMID 41057328

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a decreasing trendno p-value reported

We respectively prepared Mn-mRNA with mSpike (4k nt), mLuc (1.9k nt), mOVA (1.6k nt), and mEGFP (1k nt) to verify the universality of the preparation conditions (65 °C heating for 5 min with 5:1 molar ratio of input Mn 2+ to bases), though the particle size of Mn-mRNA had a decreasing trend with the mRNA length increasing.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.