Barely Significant
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Examining Differences in Pathological Outcomes and Safety for Prostate Cancer Patients Undergoing Either Subcapsular Orchiectomy or Medical Androgen Deprivation Therapy: A Systematic Review.

F1000Res · 2025 · PMC12504932 · PMID 41070109

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a slight trendno p-value reported
Follow-up evaluations revealed a slight trend toward reduced psychological distress in patients receiving hormonal treatment, although no statistically significant differences in psychological outcomes were detected between the groups. 19 In 1987, Parmar et al. conducted a study revealing that the psychological distress linked to orchiectomy, the surgical removal of one or both testicles, was only marginally more significant than that experienced by patients receiving alternative treatments.

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