Assuming an increasing trend, we represent the relationship between the dose and the probabilities of negative responses using the function F ( x ), where x denotes the magnitude variable of the dose (Fig. 3 ).
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Determination of the 50% and 95% effective dose of esketamine combined with propofol for intravenous sedation in pediatric circumcision: study protocol for a randomized controlled, double-blind, dose-finding clinical trial.
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