Potential vulnerability and resilience to accelerated brain aging in women exposed to stressful life events: insights from the brain age prediction model.

Neurobiol Stress · 2025 · PMC12508567 · PMID 41080803

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

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boldest claim

The sentences

a trend toward significancep = 0.055so close (0.05 < p ≤ 0.1)

ANCOVA identified a significant main effect of having alcohol-use symptoms on the BAG (F (1,515) = 11.69, p < 0.001), while the effect of emotional symptom presence showed a trend toward significance (F (1,515) = 3.70, p = 0.055).

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marginal significanceno p-value reported

Nonetheless, the pronounced main effect of alcohol-use symptoms on BAG, contrasted with the marginal significance of emotional symptoms, is consistent with prior evidence suggesting a stronger influence of alcohol use on brain aging.

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