A slight trend to increase of TCr (+3%) and a strong imbalance of the creatine/phosphocreatine (Cr/PCr) ratio, with a substantial raise of PCr (+20% in the hippocampus, +15% in the cortex) at the expense of Cr (−18% in the hippocampus, −20% in the cortex), was also observed in the DSS‐treated mice.
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Intestinal inflammation induces glymphatic remodeling, priming early neurodegenerative signals in male mice.
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