SnRNA-seq Interprets Mechanisms by which Three Glial Cell Types Influence Myelin Regeneration in Adult Drug-Resistant Epilepsy-Related Cognitive Impairment.

Mol Neurobiol · 2025 · PMC12511217 · PMID 40676367

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Differentiation and Transcriptional Regulation of OPCs in Cognitive Disorders Analysis of the proposed temporal trajectory of OPCs to OLs showed an overall trend of differentiation from OPCs to OLs, with OPCs represent the initial state in pseudotime, while OLs occupy the terminal differentiation state (Fig. 4 A, C ).

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