Barely Significant
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Role of Vitamin D Supplementation in Chronic Liver Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Nutr Rev · 2025 · PMC12512233 · PMID 40644459

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marginally significantno p-value reported
The results for ALP were marginally significant (MD, −7.53; 95% CI, −15.77 to 0.72).

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an increasing trendno p-value reported
Ye et al demonstrated an increasing trend in global cirrhosis-related mortality of 47.15% from 1990 to 2017. 1 The most pronounced increase was detected in countries with a middle or high sociodemographic index and Eastern Europe, where unfavorable trends in cirrhosis-related mortality are driven by lifestyle-modifiable etiologies such as alcohol-related liver disease (ALD) or non-alcoholic fatty liver disease (NAFLD).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.